ФИЗИОЛОГИЧЕСКАЯ АКТИВНОСТЬ НИТРОФУРАНОВЬІХ СОЕДИНЕНИЙ С ПРОСТЬІМИ ЗАМЕСТИТЕЛЯМИ

Abstract The relationship between the bactericidal, fungicidal and herbicidal activity and the structure of nitrofuranoic compounds was investigated. The nitro, halo and oxime groups in the α -position of α -nitrofurane increase, and the carbamyl group strongly decreases the antibacterial activity; other substituents have no influence. The introduction of substituents in the β -position gives compounds of strongly diminished or no activity at all. In general, antifungal activity does not change in line with antibacterial activity. Herbicidal activity was determined by acting with nitrofuranoic compounds on wheat and cucumber. The introduction of β -substituents does not lower the activity, whereas the introduction of α -substituents does.