Abstract 12473: A Novel Selective EP4 Receptor Agonist Improves Intracellular Ca2+ Handling and Cardiomyocyte Function in Intact Failing Cardiomyocytes

Wakako Murakami,Shigeki Kobayashi,Takeki Myoren,Shigehiko Nishimura,Takayoshi Kato,Masakazu Fukuda,Makoto Ono,Hiroki Tateishi,Mamoru Mochizuki,Tetsuro Oda,Shinichi Okuda,Takeshi Yamamoto,Masafumi Yano

Abstract 12473: A Novel Selective EP4 Receptor Agonist Improves Intracellular Ca2+ Handling and Cardiomyocyte Function in Intact Failing Cardiomyocytes

2013

Wakako Murakami
Shigeki Kobayashi
Takeki Myoren
Shigehiko Nishimura
Takayoshi Kato
Masakazu Fukuda
Makoto Ono
Hiroki Tateishi
Mamoru Mochizuki
Tetsuro Oda
Shinichi Okuda
Takeshi Yamamoto
Masafumi Yano

Background: Prostaglandin E2 (PGE2) has four receptor subtypes, EP1-EP4. EP4 is reported to be a dominant receptor subtype expressed in cardiac tissue. However, the precise role of EP4 receptor in ...

Keywords:

EP4 Receptor
Internal medicine
Diabetes mellitus
Intracellular
Cardiology
Agonist
Pharmacology
Medicine
Prostaglandin E2
receptor subtype
calcium handling
Receptor

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