The carboxylesterases/amidases of mammalian liver and their possible significance.

AbstractWith regard to the acyl moiety, carboxylesterases preferentially split esters of short-chain carboxylic esters. With most carboxylesterases the maximum of the reaction rate is found at an acyl chain length of C3 to C624,77,170,303 (see Section 5.4). However, there are some reports of carboxylesterases acting on medium- and long-chain fatty acid esters as well.143,189,252,253