Correlation between body mass index and placement error in cervical cancer radiotherapy

Objective To investigate the correlation between body mass index (BMI) and placement error in cervical cancer radiotherapy. Methods A total of 88 patients with cervical cancer who underwent radiotherapy in Peking University Cancer Hospital from June 2018 to May 2019 were randomly selected. They were divided into the 28 patients(BMI≥25kg/m2) in the observation group and 60 patients (BMI<25 kg/m2) in the control group according to the BMI. The placement error and tumor control probability of the two groups were recorded and compared. Results The placement errors of the observation group in the X-axis, Y-axis and Z-axis directions were (8.83±3.10)mm, (5.45±3.12)mm, and (6.24±3.13)mm, respectively, which were higher than those in the control group (P<0.05). The tumor control probability (15.44±3.10)% of the observation group was less than that of the control group (18.56±4.19)%, P<0.05. Conclusions There are significant correlation between BMI and placement error in cervical cancer radiotherapy, and increase in BMI can lead to increase in the placement error, resulting in decrease in tumor control probability. Key words: Cervical cancer; Radiotherapy; Body mass index; Placement error