INFLUENCE OF ESTIMATION OF INTER-OCCASION VARI ABILITY ON DETECTION OF TIME-VARYING COVARIATES

ABSTRACT METHODS a (mean ± SD) ∆ df b p-value CL Body Weight 1025 ± 44.3 2 < 0.0001 CL Time on Therapy 560.6 ± 38.9 3 < 0.0001 V Body Weight 457.2 ± 69.0 1 < 0.0001 CL Body Weight 631.9 ± 38.9 2 < 0.0001 CL Time on Therapy 563.3 ± 59.8 3 < 0.0001 V Body Weight 419.3 ± 65.2 1 < 0.0001 IOV