Chronic Inflammation After TBI and Associated Behavioral Sequelae

Traumatic brain injury (TBI) is associated with peripheral and central inflammatory processes that contribute to injury pathology and functional recovery. Unfortunately, there are no effective therapies for limiting either the immediate or long-term neurological consequences of TBI. The purpose of this review is to briefly summarize the relevant TBI pathophysiology and current clinical strategies to reduce inflammation, and to discuss the role of ongoing inflammatory processes that may contribute to long-term neuropsychiatric complications associated with TBI.