Recent progress in post-renal transplantation diabetes mellitus

Post-renal transplantation diabetes melltus(FIDM)has grown to be given more attention due to a wide range of complications including rejection,sepsis,higer number of graft loss,increased mortality and cardiovascular events.The incidence is about 2%-50%.Race,age,gender,genetic risk factors,bedyweight,rejection episodes and immunosuppressive drugs have been identified as risk factors for PTDM.Among several risk factors predisposing to PTDM,immunosupprossive drugs play major roles in the pathogenesis.Most patients start on oral antidiabetic drugs and insulin.Prevention strategies include close minitoring before and after transplantation,lifestyle intervention,corticosteroid-sparing regimen and optimization of immunosuppressive therapy. Key words: Post-renal transplantion diabetes mellitus; Immunosuppressive drugs