Budd-Chiari syndrome associated with hepatocellular carcinoma:a report of 10 cases

Objective To investigate the clinical features,prognosis and treatments of Budd-Chiari syndrome(B-CS)associated with hepatocellular carcinoma(HCC).Methods The clinical data of 10 patients with B-CS associated with HCC treated in our hospital were retrospectively analyzed.B-CS was diagnosed by color Doppler and/or inferior veno cavagraphy and percutaneous transhepatic hepatovenography.It was of Type Ⅰa in 4 patients,Type Ⅱ in 3 and Type Ⅲ a in the left 3.HCC was diagnosed by color Doppler,SCT and pathology detection.HCC in 8 patients was resected successfully and mesocaval shunt performed in 3.The percutaneous transluminal angioplasty(PTA)was conducted in 5 patients 2-3 d before the operation.Two patients underwent PTA+TACE(transcatheter arterial chemoembolization).Results One patient died of hepatic failure on postoperative day 5.One patient with chylorrhea after operation was cured.Nine cases were followed up for 6 months to 5 years.Two patients died of hepatic failure 0.5 and 1 year after the operation,respectively.Two patients died of HCC recurrence 1 and 2 years after the operation.Conclusion The patients with B-CS associated with HCC have worse prognosis.Relieving hepatic congestion of B-CS and resecting the tumor as soon as possible is an effective method for its treatment now. Key words: Carcinoma hepatocellular; Budd-Chiari syndrome; Hepatic congestion