Optimization of ultramicro comminution technology for Forsythia suspensa by uniform design

Objective To optimize the technical parameters of ultramicro comminution for Forsythia suspensa by uniform design.Methods The scope of each comminution technology parameter was studied by using single-factor test,and the condition of ultramicro comminution technology was optimized by uniform design and stepwise regression.Results The stepwise regression equation was Y = 41.083-1.029X2,r = 0.999 8;According to the scope of each comminution technology parameter and the actual production conditions,the optimized technical conditions of ultramicro powder grinding of Forsythia suspense were as follows:grinding time 18 min,grinding temperature ?10—10 ℃,water content 5%—9%,medium filling rate 60%—70%,predicted particle diameter D50 22.56 μm,validation particle diameter D50 22.81 μm,which revealed that this equation had good practical guidance.Conclusion The relationship between ultramicro comminution technical parameters and particle diameter is very good,and the uniform design could guide the ultramicro comminution technology.