The value of wireless pH capsule monitoring in the diagnosis of laryngopharyngeal reflux

Objective To investigate the correlation between gastroesophageal reflux and laryngopharyngeal reflux(LPR)and the clincal value of wireless pH capsule monitoring in the diagnosis of LPR. Methods Tweleve patients with LPR symptoms who scored more than 13 in reflux symptoms index(RSI)test and tweleve healthy volunteers were recruited.They were required to receive RSI test and 48-hour dual wireless pH monitoring.The details of meals, sleep, activities, and discomfort were recorded.The acid exposure and the correlation of proximal and distal esophageal were analyzed. Results The LPR episodes and DMS in LPR patients were significantly higher than that in healthy volunteer group(P<0.05), in coincidence with the RSI scores.The LPR episodes were correlated with DMS in LPR patients significantly.There were not any severe side effects during monitoring. Conclusion Wireless pH capsule is effective in pH monitoring in laryngopharyngeal reflux with high accuracy, safety and tolerance. Key words: Laryngopharyngeal reflux; Wireless pH capsule