Dysnomy and Executive Processing Errors of SARS-COV-2 post-infection
2021
Introduction: The disease SARS-CoV-2, named COVID-19, was
officially declared a pandemic by the World Health Organization on March
11th, 2020. SARS-CoV-2 contains a single-stranded, positive-sense RNA
genome surrounded by an extracellular membrane containing a series of
spike glycoproteins resembling a crown. Neuropsychiatric manifestations
are common during viral pandemics but are not effectively addressed. Case
Report: We report the case of a man, 42 years old, who after the infection
by SARS-COV2, presented dysnomy, cognitive easing and errors in motor
processing. Results and Discussion: Studies have shown the neuroinvasive
capability of SARS-COV2, resulting in neurological complications.
Common neurological symptoms are headache, dizziness, anosmia,
dysgeusia, mental confusion, and muscle weakening, progressing toward
severe complications like cerebrovascular disease, seizures, muscle pain,
and Guillain-Barre syndrome. The patient in the present case, about seven
days after the initial infection, began to have difficulties in naming basic
objects and "cognitive" slowness in the performance of basic and
instrumental activities of daily life, especially those that required mutual
tasks and that required concentration. Patients may be at higher risk of
developing cognitive decline after overcoming the primary COVID-19
infection. Neuroinvasive capacities and neuroinflammatory events that may
lead to the same short- and long-term neuropathologies that SARS-CoV
had shown in human and animal models. The presence of dementia,
minimal cognitive impairment and problems with motor planning and
execution has been described. Conclusion: A structured prospective
evaluation should analyze the likelihood, time course, and severity of
cognitive impairment following the COVID-19 pandemic.
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