Effect of adjunctive application of epigallocatechin-3-gallate and ethanol-wet bonding on adhesive-dentin bonds.

Abstract Objectives To determine the effect of the combined use of epigallocatechin-3-gallate (EGCG) and ethanol–wet bonding (EWB) on resin–dentin bonds. Methods Sixty molars were sectioned, polished, and randomly divided into six groups ( n  = 10) according to the following pretreatments: group 1, water–wet bonding (WWB); group 2, WWB with 0.02% (w/v) EGCG; group 3, WWB with 0.1% EGCG; group 4, EWB; group 5, EWB with 0.02% EGCG; and group 6, EWB with 0.1% EGCG. An etch-and-rinse adhesive was then used, followed by the resin composites building. The microtensile bond strength (MTBS), failure modes and interfacial nanoleakage were separately determined after 24 h water storage or 10,000 runs of thermocycling. Results Both pretreatment method ( P  P P P Conclusion This study showed that pretreatment with 0.02% EGCG/ethanol solutions can effectively improve immediate bond strength and bond stability of etch-and-rinse adhesives on dentin. Clinical significance The adjunctive application of EGCG and EWB provides a new strategy for dentists to obtain the desired bond effectiveness during adhesive restoration in clinical practice.