Tetrahydroisoquinoline compound, preparation method and antineoplastic application thereof

The invention relates to the field of medicinal chemistry, and in particular relates to a tetrahydroisoquinoline compound with a general formula I or II, a preparation method as well as a pharmaceutical composition and an application thereof. Pharmacodynamics activity results show that the tetrahydroisoquinoline compound provided by the invention has significant antineoplastic activity and can be used for the treatment of neoplasms.