Primary cutaneous follicle center lymphoma, diffuse type, with atypical clinical features

A 33 year old male presented with an ulcerated tumor of 15 cm diameter with raised borders on the antecubital space of the right arm (figure 1A). The lesion evolved over a 2-month period and clinically resembled an expanding lesion of pyoderma gangrenosum.Hematoxylin and eosin stained sections showed an ulcerated epidermis and diffuse infiltration of cutis and subcutis with medium-sized to large neoplastic lymphoid cells (figure 1C). Most cells had cleaved or irregular nuclei with dispersed chromatin [...]