Deposition of a multilayered protein coating onto poly(ethylene terephthalate)

Using the method of the multiple repeated sorption of serum albumin and dextran sulfate, multilayered protein coatings crosslinked by glutaric aldehyde were deposited onto the surface of PET and PE films and track-etched PET membranes. The coatings were found to be stable over a wide range of pH and ionic strength. The existence of the as-formed protein coatings on the surface of polymers was proved by IR spectroscopy, and the content of protein in each layer was estimated. By measuring the contact angles for a polymer surface coated with a protein layer, hydrophilic-hydrophobic properties of the surface were shown to be changed upon deposition of each protein layer. The coating was found to have almost no effect on the hydrodynamic resistance of the track-etched membrane to the penetrant flow.