Image guiding system of high-resolution full field OCT

Optical coherence tomography is widely used in the non-invasive detection of skin cancer. We are proposing an image guiding system integrated in a full-field OCT (FF-OCT) system and an image matching algorithm to register the guiding image onto a dermoscopic image. This guiding system takes the objective optics of FF-OCT system to observe the same vision with OCT. The FOV of the guiding image and FF-OCT is 2*2mm2 and 500*500μm2 respectively. The spatial relation between OCT and the guiding image system is fixed, the OCT imaging location can also be identified. The guiding image is then matched into the clinically used dermoscopic image which has a 20*20 mm2 FOV by an image matching algorithm. The FF-OCT image can be registered on the dermoscopic image through the guiding image. This allows physicians to target the scanning area precisely in the lesion, and record the scanned point to confirm the full lesion. This invention improves the efficiency of the entire examination and allows to follow-ups the lesion at different time.