Influence of respiratory motion in body diffusion weighted imaging under free breathing (examination of a moving phantom)

2005 
: Diffusion weighted imaging (DWI) theoretically aims to detect random motion over small distances, such as Brownian motion. Therefore, breath-hold scanning has been considered the only way to acquire DWI in the body without artifacts from bulk motion. Recent reports suggest that non-breath-hold scanning is feasible. The purpose of this study was to evaluate the influence of respiratory motion on DWI using a moving phantom model. Our results showed that the difference in apparent diffusion coefficient (ADC) was less than 10% between a static phantom and a moving phantom. There was no relation between the speed and stroke of the moving phantom and the calculated ADC. The results indicate that stable motion such as calm respiration does not cause signal loss on DWI, in contrast to intra-voxel incoherent motion (IVIM). The images obtained using this method showed high resolution and signal-to-noise ratio (SNR), suitable for three-dimensional display of the lesion.
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