РОЛЬ ПОЛИМОРФИЗМОВ PRO12ALA И C1431T PPARγВ РАЗВИТИИ ЭНДОКРИННОЙ ОФТАЛЬМОПАТИИ

AIM: to examine the association of polymorphisms Pro12Ala and C1431T PPARγwith the development of thyroid eye disease (TEO). Materials and methods. A total of 88 people: 52 patients with TEO, 36 – healthy individuals. Identified polymorphisms Pro12Ala and C1431T PPARγby PCR. Results. In more common TEO homozygous genotypes Pro/Pro and Ala/Ala (χ 2 = 6,035, p = 0.049) and allele Ala (χ 2 = 15,062, p 2 = 28,34, p 2 = 15,06, p