A kind of method for preparing Levetiracetam

2016 
The present invention relates to a kind of preparation methods of Levetiracetam, using 2 amino-butanamide hydrochlorides of L as raw material, under alkaline condition, make itself and 4 neoprene acid esters one pot reactions, complete nucleophilic displacement of fluorine and ring closure reaction, obtain Levetiracetam finished product.The method of the present invention is easy to operate, at low cost, simple to equipment requirement, safety and environmental protection, is suitble to industrialization large-scale production.
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