Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes
2020
An oxidative radical cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with hydrocarbons is described. The present reaction exhibits a wide substrate scope, and toluenes, ethers, aliphatic alcohols and simple alkanes can be employed as coupling partners, provides a access to alkyl substituted pyrido[4,3,2-gh]phenanthridines.
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