Long-term experience with bezafibrate in different types of hyperlipidemia

Bezafibrate has been shown in several studies to have effective hypocholesterolemic and hypotriglyceridemic activity |1–6|. Thus the drug may be of benefit in primary and secondary prevention of atherosclerosis. From this point of view, two aspects seem to be of particular interest. The first one is the effect of the drug on lipoprotein subfractions that are believed to play different roles in atherogenesis. The second one is the long-term effectiveness and safety of bezafibrate therapy since the hypolipidemic treatment must be continued for years or decades.