Abstract 14326: Left Ventricular Unloading Preserves Energy Substrate Utilization and Protects the Functional Integrity of Mitochondrial Complex I in Preclinical Models of Ischemia With and Without Reperfusion

Lija Swain,Xiaoying Qiao,Lara Reyelt,Aditya Chennojwala,Shreyas Bhave,Michael T. Chin,Corinne Thomas,Shiva Annamalai,Paige Crowley,Navin K. Kapur

Abstract 14326: Left Ventricular Unloading Preserves Energy Substrate Utilization and Protects the Functional Integrity of Mitochondrial Complex I in Preclinical Models of Ischemia With and Without Reperfusion

2019

Lija Swain
Xiaoying Qiao
Lara Reyelt
Aditya Chennojwala
Shreyas Bhave
Michael T. Chin
Corinne Thomas
Shiva Annamalai
Paige Crowley
Navin K. Kapur

Mechanical unloading before reperfusion limits infarct size in preclinical models and is currently under clinical investigation in acute myocardial infarction (AMI). The impact of left ventricular ...

Keywords:

Ischemia
Diabetes mellitus
clinical investigation
functional integrity
Cardiology
Myocardial infarction
Medicine
Internal medicine
Mitochondrion
Mitochondrial Complex I
infarct size

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