MicroRNAs as Biomarkers for Prediction of Environmental Health and Toxicity: A Systematic Overview
2020
MicroRNAs regulate gene expression, and their diverse roles in the field of biomedicine are established and progressively increasing along with advancements in molecular biology techniques. The environment affects human health via genetic and epigenetic alterations. The study of cellular or circulating biomarkers offers help in the management of environmental toxicology by predicting environmental risk factors of any nature, such as air, metals and pesticides and other chemicals. Here, we review on the relationship of microRNAs as biomarkers and the toxicology of environmental agents. Concerning the effects of toxic agents in the environment and prediction of human exposure by biomarkers are still ongoing processes. It demands further researches using advanced research tools. Moreover, the studies dealing with toxicology-related miRNA changes and biomonitoring of environmental xenobiotics with altered miRNA expression will be highlighted in this review.
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