The Bioactive Compounds of Avicenia sp Stem ExtractImproved the Viability of Fish Challenged with Aeromonas hydrophila
2018
Abstract: Aeromonas hydrophila is one of bacteria as major diseases for the Motile Aeromonads Septicemia
(MAS). The aims of this research to get a substance which potential as bioactive of stems bark of Avicennia
sp. for increase fish viability which exposed of A. hydropila. The samples were extracted by using ethanol
70% and then evaluated of antibacterial activities by paper disk diffusion agar technique. The active
extracts were partial purified by chromatography column. The fraction of substance was show activities
against bacteria analyzed by GC-MS. The results were found four peak and predicted as (1) 2-propenoic
acid, 3-[3, 4-dimethoxyphenyl]-methyl ester (2) 3, 4-dimethoxycinnamic acid, (3) 1, 1-dimethyl guanidine
(4), Methyl 10-oxostearate. The active fraction was isolated from stem bark of Avicennia sp. should be
further studied in animal models for in vitro efficacy and toxicity. The percentage of in vivo towards test
fish viabilities showed the difference between treated and untreated. The percentage of viability ranged
from 35 to 83.33% while control was 91.67%. Based on finding, we suggest that Avicenia sp. bark extract
was increasing of fish viability
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