Abstract 12591: STAT3 Activation Prevents Mesenchymal Stem Cell Apoptosis and Improves Infarct Repair

Yu-Ting Xuan,Yanqing Zhu,Ou-Li Wang,Guangming Cheng,Harold Elias,Arash Davani,Yanjuan Yang,Magdy Girgis,Robert J. Vincent,Jeryl Hauptman,Buddhadeb Dawn

Abstract 12591: STAT3 Activation Prevents Mesenchymal Stem Cell Apoptosis and Improves Infarct Repair

2012

Yu-Ting Xuan
Yanqing Zhu
Ou-Li Wang
Guangming Cheng
Harold Elias
Arash Davani
Yanjuan Yang
Magdy Girgis
Robert J. Vincent
Jeryl Hauptman
Buddhadeb Dawn

The role of STAT3 in mesenchymal stem cell (MSC) biology remains unclear. We hypothesized that STAT3 activation would prevent MSC apoptosis, promote angiogenesis, and enhance infarct repair. Treatm...

Keywords:

STAT3
Apoptosis
Angiogenesis
Myocardial infarction
Stem-cell therapy
Mesenchymal stem cell
Internal medicine
Cell signaling
Cardiology
Cancer research
Medicine
Diabetes mellitus

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