Massive intravascular hemolysis in a patient infected by a Clostridium perfringens.
2006
Clostridium perfringens infection is a very rare cause of massive intravascular hemolysis, but it
should always be kept in mind, since only early treatment can rescue patients from an otherwise rapidly
fatal outcome. We report a case of a 78-year-old diabetic male who was admitted complaining of
general fatigue, dark red urine, and vomiting. His blood revealed massive hemolysis. Computer
tomography demonstrated huge liver abscess in the right lobe of the liver. About 1 h after admission,
he suddenly fell into a critical condition. He died 3 h after admission in spite of intensive care and
resuscitation. Clostridium perfringens was detected from the blood taken before death and from
liver abscess by biopsy after death. We concluded that this patient died of acute massive intravascular
hemolysis in septicemia caused by Clostridium perfringens infection.
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