Comparative Evaluation of Inter Appointment Pain and Analgesic Intake with Calcium Hydroxide and Triple Antibiotic Paste As Intracanal Medicaments In Patients With Apical Periodontitis – A Randomized Controlled Single-Blinded Clinical Trial : Interappointment and analgesic intake on using two different medicaments

Objective: This study aimed to evaluate the effect of calcium hydroxide and triple antibiotic paste as intracanal medication on the interappointment pain at 8, 24, and 48 hours postoperatively in patients with symptomatic apical periodontitis undergoing multiple visit root canal treatment. Materials and Methods: Two hundred and seven systemically healthy patients under the age group of 18-45 years with mandibular molars presenting with symptomatic apical periodontitis which require root canal treatments were included in this study. After access cavity preparation, cleaning and shaping was done till ISO 25 size file, and the patients were randomized into three groups (each group of 69 samples). Group I: no medicament, group II: calcium hydroxide and group III: triple antibiotic paste (TAP). Postoperative pain was evaluated at 8 hours, 24 hours and 48 hours. Results: The results showed that at 8 hours, 24hours and 48hours, there was a statistical difference between I and III (p 0.05). Conclusion: Within the limitations of this study, TAP was more effective than calcium hydroxide in relieving pain and reducing the analgesic intake at the first 24hours.   KEYWORDS Intracanal medicament; Calcium hydroxide; Triple antibiotic paste; Interappointment pain; Apical periodontitis.