CDKN2A alterations as markers of immune checkpoint blockade (ICB) resistance in urothelial carcinoma (UC).

Amin Nassar,Elio Adib,Elie W. Akl,Sarah Abou Alaiwi,Pier Vitale Nuzzo,Tarek H. Mouhieddine,Guru Sonpavde,Robert I. Haddad,Marios Giannakis,F. Stephen Hodi,Toni K. Choueiri,David J. Kwiatkowski

CDKN2A alterations as markers of immune checkpoint blockade (ICB) resistance in urothelial carcinoma (UC).

2021

Amin Nassar
Elio Adib
Elie W. Akl
Sarah Abou Alaiwi
Pier Vitale Nuzzo
Tarek H. Mouhieddine
Guru Sonpavde
Robert I. Haddad
Marios Giannakis
F. Stephen Hodi
Toni K. Choueiri
David J. Kwiatkowski

475Background: ICB has shown clinical benefit across several metastatic carcinomas; however, predictive biomarkers are still lacking. CDKN2A is one of the most commonly altered genes across human c...

Keywords:

Cancer research
Blockade
CDKN2A
Gene
urothelial carcinoma
Medicine
Immune checkpoint
predictive biomarker

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