Slow integration leads to persistent action potential firing in distal axons of coupled interneurons

The authors report that, in a subset of rodent hippocampal and neocortical interneurons, evoking hundreds of spikes at normal rates caused persistent firing that outlasted the stimulus by about a minute. Persistent firing was generated in the distal axon, did not require somatic depolarization and could be shared between interneurons via an axo-axonal interaction.