ENDOTHELIUM-DEPENDENT VASCULAR REACTIVITY IN DIABETES MELLITUS TYPE 2

The review presents modern information on the development of disorders of endothelium-dependent vascular reactivity in diabetes mellitus (DM) type 2. In type 2 DM, disorders of endothelium-dependent vascular reactivity associated with hyperglycemia and oxidative stress, manifesting by a reduced vascular response to vasodilators and pressor (paradoxical) vascular reactions to them, directly associated with cardiovascular events are observed.