Process for the preparation of carboxamides pyrazole

2010 
A process for the preparation of the compound of formula I: which process comprises: a) reacting the compound of formula II: in the presence of a catalyst in a suitable organic solvent with the compound of formula III to the compound of formula IV: b) hydrogenating the compound of formula IV in the presence of a metal catalyst to the compound of formula V: c) reducing the compound of formula V in the presence of a reducing agent to the compound of formula VI: d) dehydrating the compound of formula VI in the presence of an acid compound of formula VII: e) reacting the compound of formula VII with hydroxylamine compound of formula VIII: f) acylating the oxygen of the oxime of the compound of formula VIII in the presence of a solvent and an acylating agent and finally reacting the product obtained with the compound of formula IX: or ff) reacting the compound of formula VIII with an excess of the compound of formula IX.
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