Therapeutic Management of Ketosis Associated with Sub-clinical Mastitis in Transition Cows

Present research records the association between sub-clinical mastitis and sub-clinical ketosis in apparently healthy early lactating cows. All cows were subjected to california mastitis test and cultural tests for confirmation of sub-clinical mastitis. Subclinical ketosis was identified based on serum BHBA levels (more than 1.40 mmol/L). Out of 62 cattle with subclinical mastitis, 28 were found to be having sub-clinical ketosis. In vitro drug sensitivity test was conducted on 62 whole milk cultures which revealed that sensitive to Enrofloxacin and Ceftriaxone with Tazobactum. 28 animals were divided into two groups and therapy was given with antibiotics (Enrofloxacin and Ceftriaxone with Tazobactam) along with Meloxicam and Chlorpheniramine maleate for both groups. For group-A cows were treated with additional supplementation of oral glucogenic precursor with Cyanocobalamin and Nicotinamide. After treatment both groups of animals were tested for serum BHBA levels and milk for cultural examination at 1st week and 2nd week of post therapy. Significant reduction in serum BHBA values recorded in group-A animals than compare with group-B animals after completion of therapy. Present study reports the effect of oral gluconeogenic precursor, cyanocobalamin and nicotinamide in the treatment of subclinical ketosis in cows.