Creatine kinase and brain energy metabolism : function and disease

This volume includes the proceedings of a NATO-sponsored advanced research workshop on the physiology of the creatine kinase catalyzed reaction in brain bioenergetics and on the pathophysiology of neurologic and psychiatric diseases. The workshop was held in Tbilisi, Georgia in June 2001. Topics include: the creatine kinase systems in the brain, heart and muscle; the creatine transporter in the brain; nd disorders of creatine and ATP metabolism. The book should be of particular interest to: cell biologists interested in bioenergetics and the physiology of the CK catalyzed reaction in brain and other excitable tissues; neurobiologists interested in the physiology of the CK catalyzed reaction in brain, paediatricians interested in metabolic diseases affecting ATP metabolism and creatine metabolism and transport; and neurologists interested in the effects of creatine in neurodegenerative diseases.