A novel model for treatment of hypertrophic pachymeningitis.

Yiwen Cui,Katsuhisa Masaki,Xu Zhang,Ryo Yamasaki,Takayuki Fujii,Hidenori Ogata,Shotaro Hayashida,Hiroo Yamaguchi,Fuminori Hyodo,Hinako Eto,Sachiko Koyama,Kyoko Iinuma,Tomomi Yonekawa,Takuya Matsushita,Mari Yoshida,Kazunori Yamada,Mitsuhiro Kawano,Marie Malissen,Bernard Malissen,Jun-ichi Kira

A novel model for treatment of hypertrophic pachymeningitis.

2019

Objective Immunoglobulin (Ig)G4‐related disease is a major cause of hypertrophic pachymeningitis (HP), presenting as a progressive thickening of the dura mater. HP lacks an animal model to determine its underlying mechanisms. We developed a suitable animal model for the treatment of HP.

Keywords:

Biology
Cell growth
Receptor
Dura mater
Linker for Activation of T cells
Chemistry
Downregulation and upregulation
CD3
Pathology
Transforming growth factor
Antibody

Correction
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