Abstract 11250: Long-term Outcomes for Patients With Atrial fibrillation and a Rapid Ventricular Response: A Comparison of Those With Reduced Versus Preserved Ejection Fraction at Initial Hospitalization

Background: Patients presenting with new onset atrial fibrillation with rapid ventricular response (AFRVR) may present with a reduced left ventricular ejection fraction (LVEF). We hypothesized that these patients have worse outcomes than patients presenting with preserved LVEF. Methods: Retrospective cohort study of 385 consecutive patients with new onset AFRVR, presenting between 01/2006 and 08/2014. Patients with a history of coronary artery disease or known cardiomyopathy were excluded. Patients were divided into those with reduced EF (REF) (LVEF ≤ 55%, n=147), and those with a preserved EF (PEF) (LVEF> 55%, n=238). Echocardiographic parameters, stroke rates, all-cause, and cardiovascular mortality were compared at baseline and a minimum of 1 year follow-up. Results: Mean age was 68 +/- 1.1 in REF versus 60 +/- 7.4 in PEF (p=0.39). There were no significant differences in baseline comorbidities. Mean LVEF was 47.7+/- 0.8% in REF vs 65.5 +/- 0.3% in PEF. The average duration of follow-up was 2.8 years. ...