Validation of software collimation for the calibration of monolithic PET detector modules

Monolithic detectors for positron emission tomography (PET) are an attractive alternative to traditional pixelated scintillator modules. However, the calibration of monolithic PET detector modules is more complicated than for their pixelated counterparts. The recently proposed method of software-collimated calibration for monolithic PET detectors promises to be competitive against traditional hardware-collimation calibration setups. Software collimation requires less hardware, is easier to implement, and has the potential to be used in an assembled PET scanner. In addition to the validation of the software-collimated set-up, we are proposing two different alternatives for the data calibration namely, the PC3 methods and Voronoi diagrams.