Novel Oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone and Pharmaceutical Compositions thereof

2008 
The present invention relates to a novel oxazolidinone compound having a novel oxazolidinone derivative, particularly a cyclic amino doksim or cyclic amidrazone of formula (1). Formula 1 The invention also relates to a pharmaceutical composition for antibiotic containing acceptable salts novel oxazolidinone derivatives, their prodrug, hydrate, solvate, isomers and chemical counter drugs thereof of formula (I) as an active ingredient. The novel oxazolidinone derivatives, acceptable salt thereof, a prodrug thereof, a hydrate thereof, solvate thereof, isomers and chemical counter drugs thereof according to the present invention is wide antimicrobial spectra of resistant bacteria, was toxicity is low, the gram-positive and gram exhibits a strong antimicrobial effect on bacteria, it may be useful as antibiotics. Oxazolidinone, cyclic amino doksim, cyclic amidrazone, antibiotics, anti-bacterial, Gram-positive bacteria, Gram-negative bacteria
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