抵当口服液、镇肝息风汤、星蒌承气汤对脑出血模型大鼠转铁蛋白、转铁蛋白受体的影响

To investigate the immudogic metabolism of Didang Oral Solution (抵当口服液), Zhenganxifeng Decoction (镇肝息风汤) and Xinglouchengqi Decoction (星萎承气汤) on the treatment of ICH. Methods: The fresh quantitative autologous blood was infused into the right caudate nucleus of rat sterotaxically to build up experiment. 72 rats with ICR were divided into 4 groups. one group were eared with Didang Oral Solution, one with Zhenganxifeng Decoction, one with Xinglouchengqi Decoction. Rats in the model group and is the control group were cured with Saline. 24, 48, 72h after operation, the rats were sacrificed and the brain tissues were made far immunohisto chemistry analysts of Tf and Tf-R. Results: Compared with the control group, the expressions of Tf and Tf-R in the model group were increased. Compared with the model group, the expressions of Tf and Tf-R in drag groups were increased after operation. The expressions of Tf in Didang Oral Solution group were increased at 48, 72h after operation, the expressions of Tf-R in durg group, were increased at 48, 72h after operation. Conclusion: The study supports the hypothesis that the expression of Tf/Tf-R with Didang Oral Solution might be the mainly metabolism of alleviate inflaonmation and encephale dema.