Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study

Wen Zhou,Yuqian Li,Lulu Zhang,Yuanyuan Shi,Chongjian Wang,Dongdong Zhang,Xuejiao Liu,Zhenxing Mao,Linlin Li

Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study

2018

Wen Zhou
Yuqian Li
Lulu Zhang
Yuanyuan Shi
Chongjian Wang
Dongdong Zhang
Xuejiao Liu
Zhenxing Mao
Linlin Li

Background The purpose of this study was to evaluate the effect of single-nucleotide polymorphisms (SNPs) of the GCKR and G6PC2 genes on risk for type 2 diabetes and the SNP-SNP and haplotype-based interactions between these genes.

Keywords:

Endocrinology
Haplotype
Lipidology
Diabetes mellitus
Internal medicine
Type 2 diabetes
Population
Type 2 Diabetes Mellitus
Biology
Bioinformatics
Nested case-control study
Single-nucleotide polymorphism
Genotype
Allele
Linkage disequilibrium
Genetics
Odds ratio
Multifactor dimensionality reduction

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