Diagnosis and treatment of paediatric multisystem inflammatory syndrome

Osszefoglalo. A SARS-CoV-2-fertőzes ritka gyermekkori szovődmenye a sokszervi gyulladas, angol terminologiaval paediatric inflammatory multisystem syndrome (PIMS). Ket vagy tobb szerv erintettsegevel jaro, sulyos tunetekkel indulo betegsegről van szo, amelynek tunetei atfedest mutatnak a Kawasaki-betegseggel, a toxikus sokk szindromaval es a makrofagaktivacios szindromaval. A PIMS-betegek intenziv terapias osztalyon vagy intenziv terapias hatterrel rendelkező intezmenyben kezelendők, ahol biztositottak a kardiologiai ellatas feltetelei is. A szukseges immunterapia a klinikai prezentaciotol fugg. A jelen kozlemenyben a szerzők a relevans nemzetkozi irodalom attekinteset kovetően ajanlast tesznek a PIMS diagnosztikai es terapias algoritmusara. Orv Hetil. 2021; 162(17): 652-667. Summary. Pediatric inflammatory multisystem syndrome (PIMS) is a rare complication of SARS-CoV-2 infection in children. PIMS is a severe condition, involving two or more organ systems. The symptoms overlap with Kawasaki disease, toxic shock syndrome and macrophage activation syndrome. PIMS patients should be treated in an intensive care unit or in an institution with an intensive care background, where cardiological care is also provided. The required specific immunotherapy depends on the clinical presentation. In this paper, after reviewing the relevant international literature, the authors make a recommendation for the diagnostic and therapeutic algorithm for PIMS. Orv Hetil. 2021; 162(17): 652-667.