Abstract P114: Predominance of Formation Over Degradation as Mechanism of Angiotensin-II(1-8) Regulation in Aminopeptidase a deficient Kidneys

Aminopeptidase A (APA), Angiotensin Converting Enzyme (ACE)-2, Neprilysin (NEP) and other enzymes degrade Angiotensin(Ang)-II, whereas ACE is the main AngII(1-8) forming enzyme. Our objective was t...