Copper-catalysed oxidative α-C(sp3)–H nitroalkylation of (hetero)arene-fused cyclic amines
2020
Under aerobic copper catalysis, we herein report a direct α-C(sp3)–H nitroalkylation of N-unsubstituted (hetero)arene-fused cyclic amines with nitroalkanes. The transformation proceeds with good substrate and functional group compatibility, high step and atom efficiency, and operational simplicity.
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