The imaging changes of premature infants with periventricular leukomalacia and its influence on prognosis

Periventricular leukomalacia(PVL) is the most distinctive and characteristic brain injury in premature infants, which may result in nervous system sequelae, and affect motor development and quality of life of the infants.PVL lacks specific symptoms and the diagnosis of PVL depends on imagine.Transcranial ultrasound could make initial diagnosis and prognostic evaluation for PVL.Combined with MRI, it can assess the degree of the white matter damage and predict the possible adverse consequences, which could provide evidence for early treatment.The changes of brain imaging and their impact on the prognosis of PVL in preterm newborn was reviewed in this article. Key words: Premature infants; Periventricular leukomalacia; Imagine; Prognosis