Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population

Soo-Yon Rhee,Dana S. Clutter,W. Jeffrey Fessel,Daniel Klein,Sally Slome,Benjamin A. Pinsky,Julia L. Marcus,Leo B. Hurley,Michael J. Silverberg,Sergei L. Kosakovsky Pond,Robert W. Shafer

Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population

2019

Soo-Yon Rhee
Dana S. Clutter
W. Jeffrey Fessel
Daniel Klein
Sally Slome
Benjamin A. Pinsky
Julia L. Marcus
Leo B. Hurley
Michael J. Silverberg
Sergei L. Kosakovsky Pond
Robert W. Shafer

Background There are few large studies of transmitted drug resistance (TDR) prevalence and the drug resistance mutations (DRMs) responsible for TDR in the United States.

Keywords:

Drug resistance
Immunodeficiency
Virology
Nucleoside Reverse Transcriptase Inhibitor
Virus
Molecular epidemiology
Population
Medicine
RNA-Directed DNA Polymerase
Mutation
Reverse transcriptase
Confidence interval
human immunodeficiency virus
Resistance mutation
Odds ratio

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