AB1306 PILOT STUDY OF ADHERENCE IN PATIENTS WITH RHEUMATOLOGICAL DISEASES AUTOIMMUNE

Background: Data on adherence in patients with autoimmune rheumatological diseases are limited. Objectives: To analyze the adherence to treatment in patients with autoimmune rheumatological diseases. Methods: A cross-sectional study was performed in patients from the Complexo Hospitalario Universitario de Pontevedra with diagnosis of systemic lupus erythematosus (SLE), Sjogren’s Syndrome (SS) and Systemic Sclerosis (SE). The patients filled an anonymous survey that included data about demographic, diagnosis and treatment. Adherence to treatment was assessed using the Spanish Compliance Questionnaire in Rheumatology (sCQR). [1] Likewise, a linear regression analysis was carried out in order to identify factors related to adherence to treatment. A significant value was considered as p Results: A total of 44 patients participated in the study, although 90.9% of the surveys carried out could be used for the analysis. A total of 25 (62.5%) SLE, 9 (22.5%) SS and 6 (15.0%) SE patients participated. There were 82.5% of women and the mean age was 48.9 ± 12.8 (See Table 1). According to the sCQR 82.5% were compliant patients. None of the studied variables was associated with the adherence rate: sex (p = 1.000), age (0.134), time of evolution (p = 1.000), level of education (p = 0.677), marital status (0.392), illness (p = 1.000), number of drugs ingested per day (p = 0.873), treatment with steroids (p = 0.679) or antimalarials (p = 1.000). Conclusion: The adherence rate in our cohort was 82.5% higher than previously reported in other studies. [2,3] The sCQR could be a useful and easy-to-apply tool for the study of adherence in these patients. References [1] Salgado E, Maneiro Fernandez JR, Souto Vilas A, Gomez-Reino JJ. Correction to: Spanish transcultural adaptation and validation of the English version of the compliance questionnaire in rheumatology. Rheumatol Int 2018. [2] Feldman CH, Yazdany J, Guan H, Solomon DH, Costenbader KH. Medication nonadherence is associated with increased subsequent acute care utilization among Medicaid beneficiaries with systemic lupus erythematosus. Arthritis Care Res 2015;67:1712–21. [3] Alsowaida N, Alrasheed M, Mayet A, Alsuwaida A, Omair MA. Medication adherence, depression and disease activity among patients with systemic lupus erythematosus. Lupus. 2018 Feb;27(2):327-332. doi: 10.1177/0961203317725585. Epub 2017 Aug 21. PubMed PMID: 28825347. Disclosure of Interests: None declared