Derivatives of 2-aryl-6-phenyl-imidazo [1,2-a] pyridines POLYSUBSTITUTED, their preparation and their application in therapeutic

Compounds of formula (1): wherein: R1 represents: a phenyl group or a naphthyl group, these groups being optionally substituted; X represents 1 to 4 identical or different substituents from one another selected from hydrogen, halogen, (C1-C10) alkyl, halo (C1-C10) alkyl, (C1-C10) alkoxy, NRaRb, cyano, nitro ,; R is in position 3, 5, 7, 8 of the imidazo [1,2-alpha] pyridine of 1 to 4 identical or different substituents from one another; R2 and R3 represent, independently of one another, a hydrogen atom, a (C1-C10) alkyl any LEMENT substituted; an optionally substituted aryl group; R2 and X may form together with the carbon atoms which carry them, a carbon ring of 5 to 7 carbon atoms; R4 represents: a hydrogen atom, a (C1-C10) alkyl optionally substituted, or an aryl group optionally substituted by one or more substituants.Utilisation in therapy and method of synthesis.