Roles of Endothelial Oxidases in Endothelium-derived Hyperpolarizing Factor Responses in Mice

Aya Takaki,Keiko Morikawa,Yoshinori Murayama,Hiroto Yamagishi,Maki Hosoya,Junko Ohashi,Hiroaki Shimokawa

Roles of Endothelial Oxidases in Endothelium-derived Hyperpolarizing Factor Responses in Mice

2008

Aya Takaki
Keiko Morikawa
Yoshinori Murayama
Hiroto Yamagishi
Maki Hosoya
Junko Ohashi
Hiroaki Shimokawa

Abstract:The endothelium synthesizes and releases several vasodilator substances, including prostacyclin, nitric oxide (NO), and endothelium-derived hyperpolarizing factor (EDHF). We have demonstrated that endothelium-derived hydrogen peroxide (H2O2) is an EDHF in animals and humans and that superox

Keywords:

NAD(P)H oxidase
Prostacyclin
Cardiology
Nitric oxide
Endothelium-derived hyperpolarizing factor
Endothelium
Internal medicine
Lipoxygenase
Biochemistry
Chemistry
Xanthine oxidase
Pharmacology
Vasodilation

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