Гистотопографические особенности гиалинового хряща дистального эпифиза бедренной кости стареющих крыс

The state of the lipid peroxidation processes and the system of antioxidative protection activity in rats of two age-grade were studied by the use of biochemical analysis. Comparing to young animals plasma of aging rats have excess of integrated indicators of oxidative stress. Research of specimens of articular cartilage of the distal epiphyse of the femur in the aging group of animals in transmitted light allowed to evolute peculiar properties of the structural organization of the hyaline cartilage lining the medial and lateral condyles within a single articular surface. Morphological peculiarities appear in statistically significant thinning of the articular cartilage of the medial condyle as compared to lateral. The observed asymmetry of the articular cartilage on the tissue level is determined by damage of its histoarchitectonics. The obtained results allow us to predict a high degree of traumatic injure of the articular cartilage of the medial condyle as compared to lateral.