A case of pneumatosis cystoides coli associated with Sjogren's syndrome

: We report a case of pneumatosis cystoides coii associated with Sjogren's syndrome. This 53-year-old woman initially developed constipation and had bloody stools while she was taking prednisolone 5 mg daily for Sjogren's syndrome. Plain abdominal X-ray revealed a gaseous pattern that resembled a bunch of grapes in the left abdomen. Endoscopic examination of the large intestine revealed numerous hemispheric cystic protrusions in the sigmoid colon and at the splenic flexure of the colon. Pneumatosis cystoides coli was thus diagnosed. Treatment included oxygen inhalation, 5 L/min for 5 hours/day. The X-ray image indicating the collection of gas cleared 17 days after starting treatment. This disorder may merit consideration in the differential diagnosis of intestinal disorders in patients with collagen disease.