Calodendroside A: a taxifolin diglucoside from the stem bark of Ochna calodendron

A new flavanone diglucoside, calodendroside A (1), was isolated from the methanolic extract of the stem bark of Ochna calodendron (Ochnaceae) and its structure elucidated as (2R,3R) taxifolin-3-O-glucosyl-(1—> 2)-glucoside by means of chemical and spectroscopic evidence including 1H-1H and 1H-13C COSY NMR. The connection of the two sugar moities was determined by the use of the heteronuclear multiple bond connectivities experiment (HMBC). To our knowledge, the present report is the first describing the isolation of a flavonoid diglucoside from a member of the Ochnaceae family.Key words: Ochna calodendron, Ochnaceae, stem bark, flavanone diglucoside, calodendroside A.